Great topic. I am left handed also. I use right handed Curado's and I cast with my right hand, switch and reel with my right hand. My partner who just got involved in baitcasters this past season, is right handed and because of always using spinning equipment with the handle on the left, he uses left handed curado's. Cast right, reels left.
My spinning gear, I cast right, don't change hands and reel left.
Vodka, my partner looks completely novice the way he fishes also but he gets the job done. As far as missing a hit from changing hands.... It's never happened. When your used to switching hands, it's so quick it's never a factor in setting the hook. Watch the pro's, 95% of them do the same thing.