I haven't tried resin or polyurethane boards for lure building. Once I switched to Azek PVC decking and trimboard (thank you John Hopkins) I stopped my lure material search. That's all I build with, except for the occasional balsa bait, because they're fun to make.
I have never fished for pike or muskie, or even seen one in person, but I have fished for barricuda, which see to have a similar set of dentures. Their teeth scratch the chrome on salt water iron, so I imagine pike and muskie will do the same. I don't know how I would make a tooth-proof lure when fishing for those guys. I'd probably just be glad I got one of my lures bit, and didn't get my own fingers bit in the process!