Sharpies are solvent based, and so are most rattle can clears.
Do a test.
Take a piece of primed wood, put a line of black sharpie on it, and then hang it or lean it so the sharpie is sitting horizontal. Be sure the sharpie is completely dry.
Then spray a light coat of the rattle can clear, any solvent based rattle can clear, over the piece. The sharpie will sag down, as the solvent in the rattle can clear dissolves part of it. With a light coat, the solvent in the clear will evaporate quickly, so it shouldn't sag too much.
Experiment with how much clear you need to get the effect you want.
You may have to try different brands of clear.
I discovered this when I used red sharpie to make gills and throat markings on my rattle can baits, and then cleared over them and hung them by the line tie.
The red ran, and it was a cool effect. Almost like flames.
You could probably get a similar effect by spraying the sharpie sample with denatured alcohol, and then letting it flash off, although I've never tried it.
With the alcohol, you could do a real light misting, and see how that looks, and then continue with another misting if you want more sag.
Just be sure you clear your lure with Createx or some other water based clear before you put the sharpie on, so the solvent won't affect the paint job. If you're using water based paints, it shouldn't be a problem.
And be sure to put another coat of water based clear over the sharpie effect when you're done, or the epoxy or other topcoat will make it run some more.