Kribman, based on your description, I don't think a thru-wire constucted that way will hold up to musky. What type of wood are you using? If you're using hard wood like maple you should be fine with just screw eyes.
Hazmail, has a nice tutorial on thru-wire constuction you should read. It will give you some great ideas on how the process is done, just expand on it for musky sized lures...
http://www.tackleunderground.com/forum/showthread.php?t=10686
Most guys use Devcon epoxy to keep it all together.
Remember "search" is your friend. Use it and you should find most of what you need to help you along the way.
As for the mesh, it would be really helpful if we knew what process you plan to use. Are you airbrushing? hand painting? foiling? spray cans?
Good luck.